Metolazone thiazide-like; Potassium-sparing diuretics; Aldosterone is a hormone produced by the adrenal gland, which activates sodium absorption and potassium removal. Metolazone - FDA prescribing information, side effects and uses The structural formula is: Metolazone is only sparingly soluble in water, but more soluble in plasma, blood, alkali, and organic solvents. General. Potassium loss. They are generally weak diuretics and work by interfering with the sodium-potassium exchange in the distal convoluted tubule of the kidneys or as an antagonist at the aldosterone receptor. . If azotemia and oliguria deteriorate during treatment of patients with severe renal disease, metolazone should be discontinued. Metolazone is used to treat high blood pressure (hypertension) and the buildup of excess fluid and salt in your body (edema). 2. The increased delivery of sodium to the distal tubular exchange site results in increased potassium excretion. Modify Therapy/Monitor Closely. Metolazone | Davis's Drug Guide Hypokalemia is dose related. View interactions for metolazone. Manufacturer advises metolazone remains effective if estimated glomerular filtration rate is less than 30 mL/minute/1.73 m 2 but is associated with a risk of . Metolazone | Drugs | BNFC | NICE Metolazone has the molecular formula C 16 H 16 ClN 3 O 3 S, the chemical name 7-chloro-1, 2, 3, 4-tetrahydro-2-methyl-3- (2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, and a molecular weight of 365.83. Complementary and Alternative Medicine - St. Luke's Hospital Metolazone And Potassium-sparing Agents | RxWiki . Skip to main content. Metolazone - an overview | ScienceDirect Topics MLA Citation "Metolazone." Davis's Drug Guide for Rehabilitation Professionals Ciccone CD. Recent studies suggest that adding spironolactone to . From the Is Metolazone Potassium Sparing appearance of the palace alone, you can see how rich the Naga royal family is. Potassium-sparing diuretics (amiloride, triamterene, spironolactone, and eplerenone) are active in the distal tubule and inhibit the exchange of sodium for potassium. Due to a large number of drugs in the T diuretics class, and the possible difference . Dosage In adults, metolazone is administered orally in a dose of 2.5-5 mg every 24 hours. Effect of interaction is not clear, use caution. Indications. Does Metolazone cause hypokalemia? - AskingLot.com
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